Luis Llamas

1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity

Karen Miller‐Moslin, Stefan Peukert, Rishi K. Jain et al. · Journal of Medicinal Chemistry · 2009 · 106 citations · Full text

Pharmaceutical Science, Antitumor Activity, Pharmacotherapy +16

Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39

Frédéric Bassilana, Adam Carlson, Jennifer DaSilva et al. · Nature Chemical Biology · 2014 · 66 citations

Signal Transduction, Receptor Gpr39, Signaling Pathway +10

Discovery of a ZIP7 inhibitor from a Notch pathway screen

Erin Nolin, Sara Gans, Luis Llamas et al. · Nature Chemical Biology · 2018 · 65 citations · Full text

Molecular Docking, Medicine, Natural Sciences +8

Bile acid analogues are activators of pyrin inflammasome

Irina Alimov, Suchithra Menon, Nadire R. Cochran et al. · Journal of Biological Chemistry · 2019 · 59 citations · Full text

Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists

Stefan Peukert, Richard L. Hughes, Jill Nunez et al. · ACS Medicinal Chemistry Letters · 2014 · 51 citations · Full text

Human Gpr39 Receptor, Diabetes Management, Pharmaceutical Science +14