R.A. Elling

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

William E. Dowdle, Beat Nyfeler, Jane Nagel et al. · Nature Cell Biology · 2014 · 715 citations

Inflammation, Cell Autophagy, Signal Transduction +13

Discovery of a potent and selective Aurora kinase inhibitor

Johan D. Oslob, M.J. Romanowski, Darin A. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 107 citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Medicine +4

Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery

Daniel A. Erlanson, Joseph W. Arndt, Mark T. Cancilla et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 84 citations

Molecular Docking, Fragment-based Drug Discovery, Drug Target +6

Structure of <i>Toxoplasma gondii </i>LDH1:  Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD⁺ Use^,

K.L. Kavanagh, R.A. Elling, David K. Wilson · Biochemistry · 2004 · 52 citations

Identification of a novel NADH-specific aldo-keto reductase using sequence and structural homologies

Eric di Luccio, R.A. Elling, David K. Wilson · Biochemical Journal · 2006 · 46 citations · Full text