Brett D. Hollingshead

Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( <i>S</i> )-2,2-Difluorocyclopropyl)((1 <i>R</i> ,5 <i>S</i> )-3-(2-((1-methyl-1 <i>H</i> -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)

Andrew Fensome, Catherine M. Ambler, Eric P. Arnold et al. · Journal of Medicinal Chemistry · 2018 · 165 citations · Full text

Sequence motifs associated with hepatotoxicity of locked nucleic acid—modified antisense oligonucleotides

Andrew D. Burdick, Simone Sciabola, Srinivasa R. Mantena et al. · Nucleic Acids Research · 2014 · 161 citations · Full text

Molecular Biology, Cell Death, Glucocorticoid Receptor +24

The hsp90 Co-chaperone XAP2 Alters Importin β Recognition of the Bipartite Nuclear Localization Signal of the Ah Receptor and Represses Transcriptional Activity

John R. Petrulis, Ann Kusnadi, Preeti Ramadoss et al. · Journal of Biological Chemistry · 2003 · 122 citations · Full text

Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells

Brett D. Hollingshead, Timothy V. Beischlag, Brett C. DiNatale et al. · Cancer Research · 2008 · 121 citations · Full text

Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver

Rushang D. Patel, Brett D. Hollingshead, Curtis J. Omiecinski et al. · Hepatology · 2007 · 80 citations