Daniel Mayhugh

N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a Novel Metabotropic Glutamate 2 Potentiator with Potential Anxiolytic/Antidepressant Properties: In Vivo Profiling Suggests a Link between Behavioral and Central Nervous System Neurochemical Changes

Matthew Fell, Jeffrey M. Witkin, Julie F. Falcone et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 99 citations

Design and Synthesis of a Potent and Selective Triazolone-Based Peroxisome Proliferator-Activated Receptor α Agonist

Yanping Xu, Daniel Mayhugh, Ashraf Saeed et al. · Journal of Medicinal Chemistry · 2003 · 61 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8

Kevin M. Gardinier, Douglas L. Gernert, Warren J. Porter et al. · Journal of Medicinal Chemistry · 2016 · 58 citations · Full text

Motor Impairment, Synaptic Transmission, Neuromodulation Therapies +25

Selectivity in palladium(0)-catalyzed cross-coupling reactions: Application to a tandem stille reaction

Stephen A. Hitchcock, Daniel Mayhugh, G. S. GREGORY · Tetrahedron Letters · 1995 · 42 citations

Asymmetric Catalysis, Chemical Engineering, Cross-coupling Reaction +8

Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake

Michael R. Pavia, Sandra J. Lobbestael, David A. Nugiel et al. · Journal of Medicinal Chemistry · 1992 · 39 citations · Full text