Stephen A. Hitchcock

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Yuan Cheng, Ted Judd, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2011 · 141 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A tandem radical macrocyclisation - radical transannulation strategy to the taxane ring system

Stephen A. Hitchcock, Gerald Pattenden · Tetrahedron Letters · 1992 · 75 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

A Convergent Total Synthesis of Calicheamicin γ

Stephen A. Hitchcock, Serge H. Boyer, Margaret Y. Chu‐Moyer et al. · Angewandte Chemie International Edition in English · 1994 · 70 citations

Pharmacy, Medicinal Chemistry, Pharmaceutics +5

Design and Preparation of a Potent Series of Hydroxyethylamine Containing β-Secretase Inhibitors That Demonstrate Robust Reduction of Central β-Amyloid

Matthew M. Weiss, Toni Williamson, Safura Babu‐Khan et al. · Journal of Medicinal Chemistry · 2012 · 64 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

A Remarkable Glycosidation Reaction: The Total Synthesis of Calicheamicin .gamma.1I

Stephen A. Hitchcock, Margaret Y. Chu‐Moyer, Serge H. Boyer et al. · Journal of the American Chemical Society · 1995 · 59 citations

Life Sciences, Biochemistry, Medicinal Chemistry +8