Xiao‐Ping Shi - Concepedia

Concepedia

Author

Xiao‐Ping Shi

United States Military Academy ORCID

Also Known As

Shi Xiaoping, X P Shi, XIAO-PING SHI, Xiao-Ping Shi, Xiao-ping Shi, Xiaoping SHI, Xiaoping Shi, Xiao‐Ping SHI, Xiao‐Ping Shi

88

Publications

3.4K

Citations

25

H-Index

69

Concepts

All Affiliations

United States Military Academy Icahn School of Medicine at Mount Sinai Peking University Beijing University of Chinese Medicine Fudan University

XS

About

Xiao‐Ping Shi is an author at United States Military Academy specializing in medicine, pharmacology, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	15	15	1.8K
2	Natural Sciences	9	9	2K
3	Biochemistry	9	9	2K
4	Engineering	1	1	33
5	Biomolecular Engineering	1	1	33

Xiao‐Ping Shi

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36

Publications

3.4K

Citations

25

H-Index

	Year	Citations
Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1 Yue‐Ming Li, Min Xu, Ming‐Tain Lai, Nature Molecular PharmacologyMedicinal ChemistryProtein SecretionPhotochemistryBiochemistry	2000	864
Presenilin 1 is linked with γ-secretase activity in the detergent solubilized state Yue‐Ming Li, Ming‐Tain Lai, Min Xu, Proceedings of the National Academy of Sciences Protein SecretionMolecular BiologyAmyloid Precursor ProteinChemical Biologyγ-Secretase Activity	2000	534
Structure-Based Design of Potent and Selective Cell-Permeable Inhibitors of Human β-Secretase (BACE-1) Shawn J. Stachel, Craig A. Coburn, Thomas G. Steele, Journal of Medicinal Chemistry Protein SecretionDrug TargetCell CultureProtein PurificationHuman β-Secretase	2004	273
Presenilin-1 and Presenilin-2 Exhibit Distinct yet Overlapping γ-Secretase Activities Ming‐Tain Lai, Elizabeth Chen, Ming‐Chih Crouthamel, Journal of Biological Chemistry	2003	168
The Pro Domain of β-Secretase Does Not Confer Strict Zymogen-like Properties but Does Assist Proper Folding of the Protease Domain Xiao‐Ping Shi, Elizabeth Chen, Kuo‐Chang Yin, Journal of Biological Chemistry	2001	123
Identification of a Small Molecule Nonpeptide Active Site β-Secretase Inhibitor That Displays a Nontraditional Binding Mode for Aspartyl Proteases Craig A. Coburn, Shawn J. Stachel, Yue‐Ming Li, Journal of Medicinal Chemistry Protein SecretionProtein AssemblyMolecular BiologyAspartyl ProteasesChemical Biology	2004	116
First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi, Journal of Pharmacology and Experimental Therapeutics	2008	105
In Vivo β-Secretase 1 Inhibition Leads to Brain Aβ Lowering and Increased α-Secretase Processing of Amyloid Precursor Protein without Effect on Neuregulin-1 Sethu Sankaranarayanan, Eric A. Price, Guoxin Wu, Journal of Pharmacology and Experimental Therapeutics	2007	100
<i>LRRTM3</i> promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease John Majercak, William J. Ray, Amy S. Espeseth, Proceedings of the National Academy of Sciences Molecular BiologySynaptic SignalingLate-onset AlzheimerAlzheimer's DiseaseBace1 Cleavage	2006	94
Discovery of Oxadiazoyl Tertiary Carbinamine Inhibitors of β-Secretase (BACE-1) Hemaka A. Rajapakse, Philippe G. Nantermet, Harold G. Selnick, Journal of Medicinal Chemistry	2006	82

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