Kuo‐Chang Yin

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 864 citations

Molecular Pharmacology, Medicinal Chemistry, Protein Secretion +12

Presenilin 1 is linked with γ-secretase activity in the detergent solubilized state

Yue‐Ming Li, Ming‐Tain Lai, Min Xu et al. · Proceedings of the National Academy of Sciences · 2000 · 534 citations · Full text

Protein Secretion, Molecular Biology, Amyloid Precursor Protein +17

The Pro Domain of β-Secretase Does Not Confer Strict Zymogen-like Properties but Does Assist Proper Folding of the Protease Domain

Xiao‐Ping Shi, Elizabeth Chen, Kuo‐Chang Yin et al. · Journal of Biological Chemistry · 2001 · 123 citations · Full text

Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs

Weirong Wang, Nancy Chen, Xiaolan Shen et al. · Drug Metabolism and Disposition · 2012 · 83 citations

Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture

Xiao‐Ping Shi, Kuo‐Chang Yin, Janet Ahern et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 1996 · 73 citations

Tumor Biology, Medicine, Pharmacology +9