Rimas J. Orentas

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

Daniel W Lee, James N. Kochenderfer, Maryalice Stetler‐Stevenson et al. · The Lancet · 2014 · 2.9K citations

Life Sciences, Hematology, Oncology +17

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Adrienne H. Long, Waleed Haso, Jack F. Shern et al. · Nature Medicine · 2015 · 1.8K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

Terry J. Fry, Nirali N. Shah, Rimas J. Orentas et al. · Nature Medicine · 2017 · 1.3K citations

Life Sciences, Immunology, Oncology +14

CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors

Robbie G. Majzner, Johanna Theruvath, Anandani Nellan et al. · Clinical Cancer Research · 2019 · 672 citations · Full text

Medicine, Immunology, Oncology +15

Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia

Waleed Haso, Daniel W. Lee, Nirali N. Shah et al. · Blood · 2012 · 583 citations · Full text

Medicine, Immunology, Oncology +9