Ross E. Longley

Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol^,

Ernst ter Haar, Richard Kowalski, Ernest Hamel et al. · Biochemistry · 1996 · 381 citations

Medicine, Oncology, Pharmacology +17

Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta

Sarath P. Gunasekera, Malika Gunasekera, Ross E. Longley et al. · The Journal of Organic Chemistry · 1990 · 372 citations

Natural Sciences, Biochemistry, Medicinal Chemistry +14

The Microtubule-Stabilizing Agent Discodermolide Competitively Inhibits the Binding of Paclitaxel (Taxol) to Tubulin Polymers, Enhances Tubulin Nucleation Reactions More Potently than Paclitaxel, and Inhibits the Growth of Paclitaxel-Resistant Cells

Richard Kowalski, Paraskevi Giannakakou, Sarath P. Gunasekera et al. · Molecular Pharmacology · 1997 · 262 citations

Medicine, Oncology, Pharmacology +17

Microcolins A and B, New Immunosuppressive Peptides from the Blue-Green Alga Lyngbya majuscula

Frank E. Koehn, Ross E. Longley, John K. Reed · Journal of Natural Products · 1992 · 179 citations

Life Sciences, Biochemistry, Immunology +9

Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin

Richard Isbrucker, Jennifer Cummins, Shirley A. Pomponi et al. · Biochemical Pharmacology · 2003 · 165 citations · Full text

Life Sciences, Biochemistry, Marine Biology +9