Mark J. Sinnamon

The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Induces Tumor Regression in a Genetically Engineered Mouse Model of PIK3CA Wild-Type Colorectal Cancer

Jatin Roper, Michael P. Richardson, Wei Vivian Wang et al. · PLoS ONE · 2011 · 140 citations · Full text

Medicine, Oncology, Pharmacology +17

Essential role for mast cell tryptase in acute experimental colitis

Matthew J. Hamilton, Mark J. Sinnamon, Gregory D. Lyng et al. · Proceedings of the National Academy of Sciences · 2010 · 124 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

A protective role of mast cells in intestinal tumorigenesis

Mark J. Sinnamon, Kathy J. Carter, Lauren Porter Sims et al. · Carcinogenesis · 2008 · 106 citations · Full text

Medicine, Immunology, Oncology +14

Mast Cell Tryptase Deficiency Attenuates Mouse Abdominal Aortic Aneurysm Formation

Jie Zhang, Jiusong Sun, Jes S. Lindholt et al. · Circulation Research · 2011 · 94 citations · Full text

Life Sciences, Immunology, Pathology +16

Analysis of Host- and Tumor-Derived Proteinases Using a Custom Dual Species Microarray Reveals a Protective Role for Stromal Matrix Metalloproteinase-12 in Non–Small Cell Lung Cancer

Heath B. Acuff, Mark J. Sinnamon, Barbara Fingleton et al. · Cancer Research · 2006 · 85 citations

Medicine, Molecular Biology, Oncology +15