Concepedia

Publication | Open Access

The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Induces Tumor Regression in a Genetically Engineered Mouse Model of PIK3CA Wild-Type Colorectal Cancer

DOIFull Paper Access

139

Citations

58

References

2011

Year

Jatin Roper, Michael P. Richardson, Wei Vivian Wang, Larissa Georgeon Richard, Wei Chen, Erin M. Coffee, Mark J. Sinnamon, Lydia Lee, Peng‐Chieh Chen, Roderick T. Bronson,
PLoS ONE

Abstract

These studies provide the preclinical rationale for studies examining the efficacy of the dual PI3K/mTOR inhibitor NVP-BEZ235 in treatment of PIK3CA wild-type CRC.

References

YearCitations

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