Markian M. Stec

Novel Vanilloid Receptor-1 Antagonists:  2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate

Elizabeth M. Doherty, Christopher Fotsch, Anthony W. Bannon et al. · Journal of Medicinal Chemistry · 2007 · 98 citations · Full text

Design and Synthesis of Peripherally Restricted Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists

Nuria Tamayo, Hongyu Liao, Markian M. Stec et al. · Journal of Medicinal Chemistry · 2008 · 62 citations · Full text

Pain Medicine, Trpv1 Antagonists, Neuropathic Pain +17

Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

Mark H. Norman, Kristin L. Andrews, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2012 · 50 citations · Full text

Chemoprevention Strategy, Molecular Biology, Clinical Candidate +19

Structure–Activity Relationships of Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Investigations of Various 6,5-Heterocycles to Improve Metabolic Stability

Markian M. Stec, Kristin L. Andrews, Shon K. Booker et al. · Journal of Medicinal Chemistry · 2011 · 43 citations · Full text

Vitro Potency, Pharmaceutical Science, Drug Target +19

Novel Vanilloid Receptor-1 Antagonists:  1. Conformationally Restricted Analogues of<i>trans</i>-Cinnamides

Mark H. Norman, Jiawang Zhu, Christopher Fotsch et al. · Journal of Medicinal Chemistry · 2007 · 42 citations · Full text

Pain Medicine, Transient Receptor Potential, Molecular Pain +17