Xidong Feng

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Adelajda Zorba, Chuong Nguyen, Yingrong Xu et al. · Proceedings of the National Academy of Sciences · 2018 · 409 citations · Full text

Engineering, Molecular Biology, Organic Chemistry +18

Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism

Nicholas G. Fox, Xiaodi Yu, Xidong Feng et al. · Nature Communications · 2019 · 160 citations · Full text

Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing

Romain Rouet, Benjamin A. Thuma, Marc D. Roy et al. · Journal of the American Chemical Society · 2018 · 152 citations · Full text

Molecular Biology, Asialoglycoprotein Receptor Ligands, Genome Engineering +17

Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue

Olugbeminiyi Fadeyi, Lise R. Hoth, Chulho Choi et al. · ACS Chemical Biology · 2017 · 134 citations

Drug Target, Bioorganic Chemistry, Molecular Biology +22

Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities

Benfang Helen Ruan, Kevin Pong, Flora Jow et al. · Proceedings of the National Academy of Sciences · 2007 · 111 citations · Full text

Immunophilin Ligands, Cell Death, Synaptic Signaling +21