Chulho Choi

Visible‐Light‐Initiated Manganese Catalysis for C−H Alkylation of Heteroarenes: Applications and Mechanistic Studies

Philippe Nuhant, Martins S. Oderinde, Julien Genovino et al. · Angewandte Chemie International Edition · 2017 · 186 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Discovery of Clinical Candidate 1-{[(2 <i>S</i> ,3 <i>S</i> ,4 <i>S</i> )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design

Katherine L. Lee, Catherine M. Ambler, David R. Anderson et al. · Journal of Medicinal Chemistry · 2017 · 145 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue

Olugbeminiyi Fadeyi, Lise R. Hoth, Chulho Choi et al. · ACS Chemical Biology · 2017 · 136 citations

Life Sciences, Biochemistry, Chemical Biology +17

Amino-oxetanes as amide isosteres by an alternative defluorosulfonylative coupling of sulfonyl fluorides

Juan J. Rojas, Rosemary A. Croft, Alistair J. Sterling et al. · Nature Chemistry · 2022 · 80 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Structurally Divergent Lithium Catalyzed Friedel–Crafts Reactions on Oxetan‐3‐ols: Synthesis of 3,3‐Diaryloxetanes and 2,3‐Dihydrobenzofurans

Rosemary A. Croft, James J. Mousseau, Chulho Choi et al. · Chemistry - A European Journal · 2016 · 72 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +14