Benjamin A. Thuma

Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing

Romain Rouet, Benjamin A. Thuma, Marc D. Roy et al. · Journal of the American Chemical Society · 2018 · 152 citations · Full text

Molecular Biology, Asialoglycoprotein Receptor Ligands, Genome Engineering +17

Discovery of a Clinical Candidate from the Structurally Unique Dioxa-bicyclo[3.2.1]octane Class of Sodium-Dependent Glucose Cotransporter 2 Inhibitors

Vincent Mascitti, Tristan S. Maurer, Ralph P. Robinson et al. · Journal of Medicinal Chemistry · 2011 · 133 citations · Full text

Pharmaceutical Science, Clinical Candidate, Pharmacotherapy +16

Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor

Carlos Sanhueza, Michael M. Baksh, Benjamin A. Thuma et al. · Journal of the American Chemical Society · 2017 · 108 citations · Full text

Drug Target, Medicinal Chemistry, Asialoglycoprotein Receptor +19

Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose

Kentaro Futatsugi, Aaron Smith, Meihua Tu et al. · Journal of Medicinal Chemistry · 2020 · 69 citations · Full text

Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK)

Kim Huard, Kay Ahn, Paul A. Amor et al. · Journal of Medicinal Chemistry · 2017 · 49 citations · Full text

Metabolic Syndrome, Medicinal Chemistry, Vivo Inhibition +14