Ralph P. Robinson

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jitske Jansen, Katharina C. Reimer, James S. Nagai et al. · Cell stem cell · 2021 · 266 citations · Full text

Medicine, Infectious Diseases, Pathology +17

Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes

Erik C. Hett, Hua Xu, Kieran F. Geoghegan et al. · ACS Chemical Biology · 2015 · 192 citations

Pharmacy, Chemical Biology, Molecular Biology +16

Identification of <i>N</i>-{<i>cis</i>-3-[Methyl(7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Michael L. Vazquez, Neelu Kaila, Joseph W. Strohbach et al. · Journal of Medicinal Chemistry · 2018 · 171 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue

Olugbeminiyi Fadeyi, Lise R. Hoth, Chulho Choi et al. · ACS Chemical Biology · 2017 · 136 citations

Life Sciences, Biochemistry, Chemical Biology +17

Discovery of a Clinical Candidate from the Structurally Unique Dioxa-bicyclo[3.2.1]octane Class of Sodium-Dependent Glucose Cotransporter 2 Inhibitors

Vincent Mascitti, Tristan S. Maurer, Ralph P. Robinson et al. · Journal of Medicinal Chemistry · 2011 · 134 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17