Jie Wu

Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate

Jie Wu, Paul Dent, Tomáš Jelı́nek et al. · Science · 1993 · 940 citations

Life Sciences, Biochemistry, Molecular Biology +14

Role of a Mitogen-activated Protein Kinase Pathway in the Induction of Phase II Detoxifying Enzymes by Chemicals

Rong Yu, Sandhya Mandlekar, Michael J. Weber et al. · Journal of Biological Chemistry · 1999 · 280 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells.

Ramadevi Nimmanapalli, Lianne Fuino, Purva Bali et al. · PubMed · 2003 · 280 citations

Life Sciences, Oncology, Pharmacology +17

Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor

Liwei Chen, Shen‐Shu Sung, M.L. Richard Yip et al. · Molecular Pharmacology · 2006 · 277 citations

Life Sciences, Molecular Biology, Pharmacology +16

Requirement for Ras/Rac1-Mediated p38 and c-Jun N-Terminal Kinase Signaling in Stat3 Transcriptional Activity Induced by the Src Oncoprotein

James Turkson, Tammy Bowman, Jalila Adnane et al. · Molecular and Cellular Biology · 1999 · 260 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15