Ramadevi Nimmanapalli

Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells.

Ramadevi Nimmanapalli, Lianne Fuino, Purva Bali et al. · PubMed · 2003 · 280 citations

Histone Modifications, Mixed-phenotype Acute Leukemia, Cell Death +18

CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl–positive human leukemia cells to apoptosis due to antileukemic drugs

Guofu Fang, Caryn Naekyung Kim, Charles Perkins et al. · Blood · 2000 · 260 citations · Full text

Geldanamycin and its analogue 17-allylamino-17-demethoxygeldanamycin lowers Bcr-Abl levels and induces apoptosis and differentiation of Bcr-Abl-positive human leukemic blasts.

Ramadevi Nimmanapalli, Erica O’Bryan, Kapil N. Bhalla · PubMed · 2001 · 246 citations

Medicinal Chemistry, Health Sciences, Antibiotics +13

Cotreatment with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) enhances imatinib-induced apoptosis of Bcr-Abl–positive human acute leukemia cells

Ramadevi Nimmanapalli, Lianne Fuino, Corinne Stobaugh et al. · Blood · 2003 · 221 citations · Full text

Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L–induced apoptosis of human acute leukemia cells

Jinghai Wen, Ramadevi Nimmanapalli, Diep Nguyen et al. · Blood · 2000 · 184 citations