Loss of Apolipoprotein E Receptor LR11 in Alzheimer Disease

Clemens R. Scherzer, Katrin Offe, Marla Gearing, +7

Archives of Neurology

CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl–positive human leukemia cells to apoptosis due to antileukemic drugs

Guofu Fang, Caryn Naekyung Kim, Charles Perkins, +4

Blood

Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis.

Caryn N. Kim, Xiaomin Wang, Yolanda Y. Huang, +4

PubMed

Ara-c-induced Mitochondrial LossChemoprevention StrategyApoptosisImmunologyCell Death +15

Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-xL

Charles Perkins, Caryn N. Kim, Guofu Fang, +1

Blood

The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.

Charles Perkins, Guofu Fang, Caryn Nae Kim, +1

PubMed

Bid ProteinsApoptosisPathologyCell DeathPaclitaxel-induced Mitochondrial Events +15

Overexpression of Bcl-2 or Bcl-xL inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells.

A M Ibrado, Yue Huang, Guofu Fang, +2

PubMed

Hematological MalignancyCell RegulationMedicineMixed-phenotype Acute LeukemiaApoptosis +11

Rab11a and Myosin Vb Regulate Recycling of the M₄Muscarinic Acetylcholine Receptor

Laura A. Volpicelli, James J. Lah, Guofu Fang, +2

Journal of Neuroscience

NAD+ and axon degeneration revisited: Nmnat1 cannot substitute for WldS to delay Wallerian degeneration

Laura Conforti, Guofu Fang, Bogdan Beirowski, +9

Cell Death and Differentiation

Neurodegenerative DiseasesNeuroregenerationDevelopmental BiologyMolecular NeuroscienceMedicine +9

"Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.

Guofu Fang, Brian S. Chang, Caryn N. Kim, +3

PubMed

Taxol-induced ApoptosisApoptosisImmunologyCell DeathTaxol-induced Cytosolic Accumulation +15

Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells.

Charles Perkins, Caryn N. Kim, Guofu Fang, +1

PubMed

ApoptosisImmunologyCell DeathCancer BiologyTumor Biology +16