Martin J. Drysdale - Concepedia

Author

Martin J. Drysdale

Also Known As

Carlosgarca-Echeverra, Drysdale, M.J., M Drysdale, M. Drysdale, M. J. DRYSDALE, M.J. Drysdale, Martin Drysdale, Martin J Drysdale, Martin J. Drysdale

199

Publications

5.3K

Citations

H-Index

Concepts

All Affiliations

Granta Design (United Kingdom)Institute of Cancer Research Cancer Research UK Cancer Research UK Scotland Institute Novartis (Switzerland)

About

Martin J. Drysdale is an author at Granta Design (United Kingdom) specializing in medicine, drug discovery, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	19	20	2K
2	Natural Sciences	15	16	1.2K
3	Biochemistry	12	12	1.4K
4	Engineering	10	10	381
5	Biomolecular Engineering	7	7	365

Martin J. Drysdale

Publications

4.8K

Citations

H-Index

Page 1

	Year	Citations
NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Cancer Research	2008	469
4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer Paul A. Brough, Wynne Aherne, Xavier Barril, Journal of Medicinal Chemistry	2007	442
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells Andrew J. Massey, D.S. Williamson, Helen Browne, Cancer Chemotherapy and Pharmacology MedicineApoptosisCell DeathSmall Molecule InhibitorHsp90 Inhibitor	2009	327
Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms Lisa Wright, Xavier Barril, Brian Dymock, Chemistry & Biology Hsp90 IsoformsSignal TransductionBiochemistryG Protein-coupled ReceptorMedicine	2004	265
Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design Brian Dymock, Xavier Barril, Paul A. Brough, Journal of Medicinal Chemistry Crystal StructureDrug TargetMolecular BiologyChemical BiologyMedicinal Chemistry	2005	231
Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design D.S. Williamson, Jenifer Borgognoni, Alexandra Clay, Journal of Medicinal Chemistry Protein ChemistryMedicinal ChemistryProtein FunctionProtein AssemblyBiochemistry	2009	222
NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models Michael Rugaard Jensen, Joseph Schoepfer, Thomas Radimerski, Breast Cancer Research	2008	222
Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-<i>d</i>]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone Paul A. Brough, Xavier Barril, Jenifer Borgognoni, Journal of Medicinal Chemistry	2009	173
Rational Design of Inhibitors of HIV-1 TAR RNA through the Stabilisation of Electrostatic “Hot Spots” Ben Davis, Mohammad Afshar, Gabriele Varani, Journal of Molecular Biology BiochemistryRational DesignNatural SciencesHuman RetrovirusAntiviral Drug Development	2004	152
Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall, Molecular Cancer Therapeutics	2007	142

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