Melanie C. Ruzek

The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation

Alexander Hooftman, Stefano Angiari, Svenja Hester et al. · Cell Metabolism · 2020 · 542 citations · Full text

Inflammation, Anti-inflammatory, Signal Transduction +12

Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages

Marah C. Runtsch, Stefano Angiari, Alexander Hooftman et al. · Cell Metabolism · 2022 · 295 citations

Inflammation, Itaconate Derivatives, Alternative Activation +13

Characterization of Early Cytokine Responses and an Interleukin (IL)-6–dependent Pathway of Endogenous Glucocorticoid Induction during Murine Cytomegalovirus Infection

Melanie C. Ruzek, Andrew H. Miller, Steven M. Opal et al. · The Journal of Experimental Medicine · 1997 · 212 citations · Full text

Endogenous Glucocorticoids Protect Against Cytokine-Mediated Lethality During Viral Infection

Melanie C. Ruzek, Bradley D. Pearce, Andrew H. Miller et al. · The Journal of Immunology · 1999 · 153 citations · Full text

NK cell functions restrain T cell responses during viral infections

Helen C. Su, Khuong B. Nguyen, Thais P. Salazar‐Mather et al. · European Journal of Immunology · 2001 · 139 citations · Full text