Melanie C. Ruzek - Concepedia

Author

Melanie C. Ruzek

Also Known As

M C Ruzek, M Ruzek, M. Ruzek, M.C. Ruzek, Melanie C Ruzek, Melanie C. Ruzek, Melanie C. Ruzek*, Melanie Ruzek, Melanie C. Ruzek

Publications

2.5K

Citations

H-Index

Concepts

All Affiliations

AbbVie (United States)Brown University Trinity College Dublin SynZyme Technologies (United States)rEVO Biologics (United States)

About

Melanie C. Ruzek is an author at AbbVie (United States) specializing in medicine, immunology, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	1.1K
2	Cell Biology	7	7	1.1K
3	Allergy	2	2	120
4	Health Sciences	1	1	10
5	Cellular Physiology	1	1	27

Melanie C. Ruzek

Publications

2.4K

Citations

H-Index

Page 1

	Year	Citations
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation Alexander Hooftman, Stefano Angiari, Svenja Hester, Cell Metabolism InflammationAnti-inflammatorySignal TransductionAutoimmune DiseaseImmunology	2020	542
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages Marah C. Runtsch, Stefano Angiari, Alexander Hooftman, Cell Metabolism InflammationItaconate DerivativesAlternative ActivationCytokineAutoimmune Disease	2022	295
Characterization of Early Cytokine Responses and an Interleukin (IL)-6–dependent Pathway of Endogenous Glucocorticoid Induction during Murine Cytomegalovirus Infection Melanie C. Ruzek, Andrew H. Miller, Steven M. Opal, The Journal of Experimental Medicine	1997	212
Endogenous Glucocorticoids Protect Against Cytokine-Mediated Lethality During Viral Infection Melanie C. Ruzek, Bradley D. Pearce, Andrew H. Miller, The Journal of Immunology	1999	153
NK cell functions restrain T cell responses during viral infections Helen C. Su, Khuong B. Nguyen, Thais P. Salazar‐Mather, European Journal of Immunology	2001	139
A modified model of graft‐versus‐host–induced systemic sclerosis (scleroderma) exhibits all major aspects of the human disease Melanie C. Ruzek, Sharda Jha, Steve Ledbetter, Arthritis & Rheumatism	2004	120
Replication of Murine Cytomegalovirus in Differentiated Macrophages as a Determinant of Viral Pathogenesis Laura K. Hanson, Jacquelyn S. Slater, Zaruhi Karabekian, Journal of Virology	1999	102
Allogeneic mesenchymal stem cells do not protect NZB × NZW F1 mice from developing lupus disease Michele Youd, Courtney E. Blickarz, Lisa Woodworth, Clinical & Experimental Immunology Cell TherapyImmunologyImmunotherapyRegenerative MedicineLupus Mouse Model	2010	93
Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4 V. Bodart, Virginia Anastassov, Marilyn C. Darkes, Biochemical Pharmacology Molecular PharmacologySmall Molecule AntagonistMedicineImmunologyMechanism Of Action	2009	55
Minimal Effects on Immune Parameters Following Chronic Anti-TGF-β Monoclonal Antibody Administration to Normal Mice Melanie C. Ruzek, Michael L. Hawes, Bruce M. Pratt, Immunopharmacology and Immunotoxicology	2003	52

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