Roberto Nuti

Novel Method for Generating Structure-Based Pharmacophores Using Energetic Analysis

Noeris K. Salam, Roberto Nuti, Woody Sherman · Journal of Chemical Information and Modeling · 2009 · 314 citations

Molecular Docking, Medicinal Chemistry, Virtual Screening +14

Ligand Binding and Functional Selectivity of <scp>l</scp>-Tryptophan Metabolites at the Mouse Aryl Hydrocarbon Receptor (mAhR)

Roberto Nuti, Marco Gargaro, Davide Matino et al. · Journal of Chemical Information and Modeling · 2014 · 45 citations

Drug Target, Ligand Binding, Toxicological Mechanism +16

Probing the Binding Site of Bile Acids in TGR5

Antonio Macchiarulo, Antimo Gioiello, Charles Thomas et al. · ACS Medicinal Chemistry Letters · 2013 · 38 citations · Full text

Proteinlipid Interaction, G-protein-coupled Receptor, Molecular Biology +16

Adamantyl-Substituted Retinoid-Derived Molecules That Interact with the Orphan Nuclear Receptor Small Heterodimer Partner: Effects of Replacing the 1-Adamantyl or Hydroxyl Group on Inhibition of Cancer Cell Growth, Induction of Cancer Cell Apoptosis, and Inhibition of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-2 Activity

Marcia I. Dawson, Zebin Xia, Tao Jiang et al. · Journal of Medicinal Chemistry · 2008 · 37 citations · Full text

Crystal Structure, Chemoprevention Strategy, Apoptosis +22

Avicholic Acid: A Lead Compound from Birds on the Route to Potent TGR5 Modulators

Roberto Pellicciari, Antimo Gioiello, Paola Sabbatini et al. · ACS Medicinal Chemistry Letters · 2012 · 36 citations · Full text

Avicholic Acid, Potent Tgr5 Modulators, Chemical Biology +16