Brandon P. Schuff

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Adelajda Zorba, Chuong Nguyen, Yingrong Xu et al. · Proceedings of the National Academy of Sciences · 2018 · 409 citations · Full text

Engineering, Molecular Biology, Organic Chemistry +18

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 318 citations

Combinatorial Chemistry, Drug Target, Thiol-reactive Covalent Inhibitors +17

Preparation, Gram-Negative Antibacterial Activity, and Hydrolytic Stability of Novel Siderophore-Conjugated Monocarbam Diols

Mark E. Flanagan, Steven J. Brickner, Manjinder S. Lall et al. · ACS Medicinal Chemistry Letters · 2011 · 70 citations · Full text

Bioorganic Chemistry, Antimicrobial Chemotherapy, Pharmaceutical Chemistry +16

Intrinsic reactivity profile of electrophilic moieties to guide covalent drug design: N-α-acetyl-<scp>l</scp>-lysine as an amine nucleophile

Upendra P. Dahal, A. Gilbert, R. Scott Obach et al. · MedChemComm · 2016 · 63 citations

Pharmaceutical Science, Drug Target, Covalent Drug Design +17

Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity

Matthew F. Brown, Mark J. Mitton‐Fry, Joel T. Arcari et al. · Journal of Medicinal Chemistry · 2013 · 63 citations

Antibiotics, Compound 17, Medicine +11