Upendra P. Dahal

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 318 citations

Combinatorial Chemistry, Drug Target, Thiol-reactive Covalent Inhibitors +17

Benchmarking <i>in Vitro</i> Covalent Binding Burden As a Tool To Assess Potential Toxicity Caused by Nonspecific Covalent Binding of Covalent Drugs

Upendra P. Dahal, R. Scott Obach, A. Gilbert · Chemical Research in Toxicology · 2013 · 67 citations

Assess Potential Toxicity, Drug Target, Pharmacotherapy +22

Intrinsic reactivity profile of electrophilic moieties to guide covalent drug design: N-α-acetyl-<scp>l</scp>-lysine as an amine nucleophile

Upendra P. Dahal, A. Gilbert, R. Scott Obach et al. · MedChemComm · 2016 · 63 citations

Pharmaceutical Science, Drug Target, Covalent Drug Design +17

Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers

Marc Payton, Brian Belmontes, Kelly Hanestad et al. · Nature Cancer · 2023 · 54 citations · Full text

Small Molecule Quantification by Liquid Chromatography-Mass Spectrometry for Metabolites of Drugs and Drug Candidates

Upendra P. Dahal, Jeffrey P. Jones, John A. Davis et al. · Drug Metabolism and Disposition · 2011 · 53 citations · Full text