Kelly Hanestad

Engineered Human IgG Antibodies with Longer Serum Half-lives in Primates

Paul R. Hinton, Mary G. Johlfs, Joanna M. Xiong et al. · Journal of Biological Chemistry · 2004 · 271 citations · Full text

AMG 900, a Small-Molecule Inhibitor of Aurora Kinases, Potentiates the Activity of Microtubule-Targeting Agents in Human Metastatic Breast Cancer Models

Tammy L. Bush, Marc Payton, Scott Heller et al. · Molecular Cancer Therapeutics · 2013 · 55 citations · Full text

Amg 900, Chemoprevention Strategy, Medicine +15

Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers

Marc Payton, Brian Belmontes, Kelly Hanestad et al. · Nature Cancer · 2023 · 54 citations · Full text

Discovery of <i>N</i>-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of Aurora Kinases with Activity against Multidrug-Resistant Cancer Cell Lines

Stephanie Geuns-Meyer, Victor J. Cee, Holly L. Deak et al. · Journal of Medicinal Chemistry · 2015 · 44 citations · Full text

Pharmacotherapy, Pharmaceutical Chemistry, Tumor Biology +19

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

Victor J. Cee, Laurie B. Schenkel, Brian L. Hodous et al. · Journal of Medicinal Chemistry · 2010 · 37 citations · Full text

Pharmaceutical Science, Chemoprevention Strategy, Kinase Inhibitors +16