Concepedia

Ignacio Aliagas

IA

22

Publications

2.3K

Citations

17

H-Index

1998

Active since

Affiliations

Shanghai Zhangjiang Laboratory(Current)

Gene Therapy Laboratory

Array BioPharma (United States)

Ignacio Aliagas is an author at Shanghai Zhangjiang Laboratory specializing in medicine, drug discovery, and pharmacology.

ORCID

Top concepts

Publications per year

1998–2022

22

Publications

22

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen et al. · Nature · 2010 · 1.6K citations · Full text

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Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-p <i>K</i> <sub>a</sub> Polar Moiety

Chudi Ndubaku, James J. Crawford, Joy Drobnick et al. · ACS Medicinal Chemistry Letters · 2015 · 81 citations · Full text

Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window

Joachim Rudolph, Lesley Murray, Chudi Ndubaku et al. · Journal of Medicinal Chemistry · 2016 · 74 citations · Full text

, , +18

Pyrazolopyridine Inhibitors of B-Raf<sup>V600E</sup>. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Steve Wenglowsky, Li Ren, Kateri A. Ahrendt et al. · ACS Medicinal Chemistry Letters · 2011 · 66 citations · Full text

Identification of <i>C</i>-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2

Mark Zak, Christopher A. Hurley, Stuart I. Ward et al. · Journal of Medicinal Chemistry · 2013 · 61 citations · Full text

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