David W.G. Wone

Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model

Anh P. Truong, G. Toth, Gary D. Probst et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 48 citations · Full text

Pharmacological Study, Biochemistry, Medicine +9

Preparation and Optimization of a Series of 3-Carboxamido-5-phenacylaminopyrazole Bradykinin B1 Receptor Antagonists

Darren Dressen, Albert W. Garofalo, Jon E. Hawkinson et al. · Journal of Medicinal Chemistry · 2007 · 35 citations · Full text

Pharmaceutical Science, Pain Medicine, N-substituted Pyrazoles +17

Design and synthesis of cell potent BACE-1 inhibitors: Structure–activity relationship of P1′ substituents

Jennifer M. Sealy, Anh P. Truong, Luke S. Tso et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 31 citations · Full text

Structure–activity Relationship, Molecular Pharmacology, Medicinal Chemistry +13

A series of C-Terminal amino alcohol dipeptide Aβ inhibitors

Albert W. Garofalo, David W.G. Wone, Angela Phuc et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 19 citations

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +7

Optimizing phenylethylphosphonamidates for the inhibition of prostate-specific membrane antigen

David W.G. Wone, Jennifer A. Rowley, Albert W. Garofalo et al. · Bioorganic & Medicinal Chemistry · 2005 · 14 citations

Medicinal Chemistry, Urology, Pharmaceutical Science +5