Oligomerized grape seed polyphenols attenuate inflammatory changes due to antioxidative properties in coculture of adipocytes and macrophages

Takuya Sakurai, Kentaro Kitadate, Hiroshi Nishioka, +7

The Journal of Nutritional Biochemistry

InflammationPolyphenolicsGrape Seed PolyphenolsMedicinePhysiology +7

Detection of Interleukin-1.BETA. in Sera and Colostrum of Dairy Cattle and in Sera of Neonates.

Masamitsu Goto, Mitsuhiro Maruyama, Kentaro Kitadate, +4

Journal of Veterinary Medical Science

Oligonol, a new lychee fruit‐derived low‐molecular form of polyphenol, enhances lipolysis in primary rat adipocytes through activation of the ERK1/2 pathway

Junetsu Ogasawara, Kentaro Kitadate, Hiroshi Nishioka, +6

Phytotherapy Research

Metabolic SyndromePrimary RatPolyphenolicsLipid SynthesisBiochemistry +12

Amelioration of abdominal obesity by low-molecular-weight polyphenol (Oligonol) from lychee

Jun Nishihira, Maremi Sato‐Ueshima, Kentaro Kitadate, +2

Journal of Functional Foods

ObesityMetabolic SyndromeBiochemistryLow-molecular-weight PolyphenolMedicine +7

Effects of Oligonol®, an oligomerized polyphenol formulated from lychee fruit, on serum concentration and urinary excretion of uric acid

Yuji Moriwaki, Chihiro Okuda, Asako Yamamoto, +6

Journal of Functional Foods

Food ChemistryOligomerized PolyphenolFood Bioactive CompoundPharmacologyPhytochemical +3

Enzyme-treated <i>Asparagus officinalis</i> Extract Shows Neuroprotective Effects and Attenuates Cognitive Impairment in Senescence-accelerated Mice

Takuya Sakurai, Tomohiro Ito, Koji Wakame, +10

Natural Product Communications

AgingLipid PeroxidationCell DeathNeurochemical BiomarkersEnzyme-treated Asparagus Extract +18

Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells

Takuya Sakurai, Kentaro Kitadate, Hiroshi Nishioka, +8

British Journal Of Nutrition

Oligonol, an oligomerized lychee fruit-derived polyphenol, activates the Ras/Raf-1/MEK1/2 cascade independent of the IL-6 signaling pathway in rat primary adipocytes

Junetsu Ogasawara, Kentaro Kitadate, Hiroshi Nishioka, +7

Biochemical and Biophysical Research Communications

Ras/raf-1/mek1/2 CascadeSignal TransductionRat Primary AdipocytesSignaling PathwayMedicine +6

Comparison of the effect of oligonol, a new lychee fruit‐derived low molecular form of polyphenol, and epigallocatechin‐3‐gallate on lipolysis in rat primary adipocytes

Junetsu Ogasawara, Kentaro Kitadate, Hiroshi Nishioka, +6

Phytotherapy Research

Thirteen-week oral dose toxicity study of Oligonol containing oligomerized polyphenols extracted from lychee and green tea

Kentaro Kitadate, Kohei Homma, Ashley Roberts, +1

Regulatory Toxicology and Pharmacology

Oligomerized PolyphenolsPolyphenolicsEnvironmental EngineeringMedicineHerb-drug Interaction +7