Seiji Miwatashi

Novel Inhibitor of p38 MAP Kinase as an Anti-TNF-α Drug:  Discovery of <i>N</i>-[4-[2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a Potent and Orally Active Anti-Rheumatoid Arthritis Agent

Seiji Miwatashi, Yasuyoshi Arikawa, Etsuo Kotani et al. · Journal of Medicinal Chemistry · 2005 · 145 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Zinc-copper(I) chloride or -silver acetate promoted coupling reaction of 2-[(Trimethylsilyl)methyl]-3-chloro-3,3-difluoropropene with carbonyl compounds. Highly efficient access to 2,2-difluoro homoallyl alcohols

Takashi Ishihara, Seiji Miwatashi, Manabu Kuroboshi et al. · Tetrahedron Letters · 1991 · 31 citations

Natural Sciences, Chemistry, Organic Chemistry +7

Design and Identification of a GPR40 Full Agonist (<b>SCO-267</b>) Possessing a 2-Carbamoylphenyl Piperidine Moiety

Hideki Furukawa, Yasufumi Miyamoto, Yasuhiro Hirata et al. · Journal of Medicinal Chemistry · 2020 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and Biological Activities of 4-Phenyl-5-pyridyl-1,3-thiazole Derivatives as Selective Adenosine A3 Antagonists

Seiji Miwatashi, Yasuyoshi Arikawa, Tatsumi Matsumoto et al. · Chemical and Pharmaceutical Bulletin · 2008 · 28 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Synthesis and Biological Activities of 4-Phenyl-5-pyridyl-1,3-thiazole Derivatives as p38 MAP Kinase Inhibitors

Seiji Miwatashi, Yasuyoshi Arikawa, Ken‐ichi Naruo et al. · Chemical and Pharmaceutical Bulletin · 2005 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17