Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

Tomohiro Yoshida, Fumihiko Akahoshi, Hiroshi Sakashita, +27

Bioorganic & Medicinal Chemistry

BiochemistryMedicineRational Drug DesignType 2Pharmacological Agent +5

Mitochondrial DNA Mutations Regulate Metastasis of Human Breast Cancer Cells

Hirotake Imanishi, Keisuke Hattori, Reiko Wada, +5

PLoS ONE

Breast OncologyMitochondrial BiologyReactive Oxygen SpeciesCancer BiologyTumor Biology +17

Strong Evidence of a Combination Polymorphism of the Tyrosine Kinase 2 Gene and the Signal Transducer and Activator of Transcription 3 Gene as a DNA-Based Biomarker for Susceptibility to Crohn’s Disease in the Japanese Population

Kayoko Sato, Mizuho Shiota, Sayaka Fukuda, +9

Journal of Clinical Immunology

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis

Kaori Ishikawa, Osamu Hashizume, Nobuko Koshikawa, +4

FEBS Letters

MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice

Takuma Tsuchida, Sayaka Fukuda, Hisanori Aoyama, +7

Lipids in Health and Disease

A case of multisystem inflammatory syndrome in children in a Japanese boy: with discussion of cytokine profile

Sayaka Fukuda, Mio Kaneta, Mayuko Miyake, +4

Modern Rheumatology Case Reports

Multisystem Inflammatory SyndromeSars-cov2 InfectionImmunodeficienciesImmunologyJapanese Boy +28

Simultaneous development of Kawasaki disease following acute human adenovirus infection in monozygotic twins: A case report

Sayaka Fukuda, Shuichi Ito, Maya Fujiwara, +4

Pediatric Rheumatology

Financial Literacy and Impulsivity: Evidence from Japan

Takuya Katauke, Sayaka Fukuda, Mostafa Saidur Rahim Khan, +1

Sustainability

Behavioral Decision MakingCognitive BiasesExperimental FinanceExperimental Decision MakingBehavioral Finance +15

Genetic variants of SMAD2/3/4/7 are associated with susceptibility to ulcerative colitis in a Japanese genetic background

Arisa Yamashita, Tatsuo Inamine, Shota Suzuki, +7

Immunology Letters

Genetic VariantsMedicinePathogenesisImmunologyGenetic Epidemiology +6

Exposures associated with the onset of Kawasaki disease in infancy from the Japan Environment and Children’s Study

Sayaka Fukuda, Shiro Tanaka, Chihiro Kawakami, +2

Scientific Reports