Mikael Altun

A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance

Dharminder Chauhan, Ze Tian, Benjamin Nicholson et al. · Cancer Cell · 2012 · 575 citations

Hematological Malignancy, Malignant Blood Disorder, Apoptosis +10

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 525 citations

Tumor Biology, Dntp Pool, Mth1 Inhibition +8

Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes

Mikael Altun, Holger Kramer, Lianne I. Willems et al. · Chemistry & Biology · 2011 · 389 citations

Proteomic Technology, Biochemistry, Natural Sciences +4

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

Mikael Altun, Henrike C. Besche, Herman S. Overkleeft et al. · Journal of Biological Chemistry · 2010 · 225 citations · Full text

Aging, Proteasome, Cytoskeleton +17

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Torkild Visnes, Armando Cázares‐Körner, Wenjing Hao et al. · Science · 2018 · 220 citations