Henrike C. Besche

Cancer Vulnerabilities Unveiled by Genomic Loss

Deepak Nijhawan, Travis Zack, Yin Ren et al. · Cell · 2012 · 236 citations · Full text

Genome Instability, Medicine, Genetics +5

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

Mikael Altun, Henrike C. Besche, Herman S. Overkleeft et al. · Journal of Biological Chemistry · 2010 · 225 citations · Full text

Aging, Proteasome, Cytoskeleton +17

Ubiquitinated Proteins Activate the Proteasome by Binding to Usp14/Ubp6, which Causes 20S Gate Opening

Andreas Peth, Henrike C. Besche, Alfred L. Goldberg · Molecular Cell · 2009 · 213 citations · Full text

Gate Opening, Protein Secretion, Protein Function +12

Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins

Henrike C. Besche, Wilhelm Haas, Steven P. Gygi et al. · Biochemistry · 2009 · 183 citations · Full text

Protein Assembly, Proteasome, Molecular Biology +17

Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

Henrike C. Besche, Zhe Sha, Nikolay V. Kukushkin et al. · The EMBO Journal · 2014 · 174 citations · Full text

Protein Function, Molecular Regulation, Medicine +10