Nikolay V. Kukushkin

Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling

Natura Myeku, Catherine L. Clelland, Sheina Emrani et al. · Nature Medicine · 2015 · 436 citations · Full text

Neurodegenerative Diseases, Protein Function, Signal Transduction +13

cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins

Sudarsanareddy Lokireddy, Nikolay V. Kukushkin, Alfred L. Goldberg · Proceedings of the National Academy of Sciences · 2015 · 234 citations · Full text

Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

Henrike C. Besche, Zhe Sha, Nikolay V. Kukushkin et al. · The EMBO Journal · 2014 · 174 citations · Full text

Protein Function, Molecular Regulation, Medicine +10

Ubiquitinated Proteins Activate the Proteasomal ATPases by Binding to Usp14 or Uch37 Homologs

Andreas Peth, Nikolay V. Kukushkin, Marc Bossé et al. · Journal of Biological Chemistry · 2013 · 103 citations · Full text

Reversion of Structure-Activity Relationships of Antitumor Platinum Complexes by Acetoxime but Not Hydroxylamine Ligands

Stefanie Zorbas‐Seifried, Michael A. Jakupec, Nikolay V. Kukushkin et al. · Molecular Pharmacology · 2006 · 59 citations