Jayne Curry

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Diana Zatreanu, Helen M.R. Robinson, Omar Alkhatib et al. · Nature Communications · 2021 · 336 citations · Full text

Fragment-Based Discovery of the Pyrazol-4-yl Urea (AT9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity

Steven Howard, Valério Berdini, John A. Boulstridge et al. · Journal of Medicinal Chemistry · 2008 · 329 citations · Full text

Drug Target, Pyrazol-4-yl Urea, Clinical Candidate +18

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Adrian L. Gill, Martyn Frederickson, Anne Cleasby et al. · Journal of Medicinal Chemistry · 2004 · 185 citations · Full text

Combinatorial Chemistry, Drug Target, Hit Identification +18

Reverse Optical Flow for Self-Supervised Adaptive Autonomous Robot Navigation

Andrew Lookingbill, John R. Rogers, David Lieb et al. · International Journal of Computer Vision · 2007 · 84 citations

Machine Vision, Engineering, Reverse Optical Flow +6

The heat shock protein 90 inhibitor, <scp>AT</scp>13387, displays a long duration of action <i>in vitro</i> and <i>in vivo</i> in non‐small cell lung cancer

Brent Graham, Jayne Curry, Tomoko Smyth et al. · Cancer Science · 2011 · 80 citations · Full text

Tumor Xenografts, Chemoprevention Strategy, Molecular Biology +17