Tomoko Smyth

Elucidation of the MD-2/TLR4 Interface Required for Signaling by Lipid IVa

Catharine M. Walsh, Monique Gangloff, Tom P. Monie et al. · The Journal of Immunology · 2008 · 119 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Inhibition of HSP90 by AT13387 Delays the Emergence of Resistance to BRAF Inhibitors and Overcomes Resistance to Dual BRAF and MEK Inhibition in Melanoma Models

Tomoko Smyth, Kim H.T. Paraiso, Keisha Hearn et al. · Molecular Cancer Therapeutics · 2014 · 91 citations · Full text

Medicine, Oncology, Pharmacology +15

Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells

Roberta Ferraldeschi, Jonathan Welti, Marissa Powers et al. · Cancer Research · 2016 · 91 citations · Full text

Life Sciences, Endocrinology, Oncology +8

The heat shock protein 90 inhibitor, <scp>AT</scp>13387, displays a long duration of action <i>in vitro</i> and <i>in vivo</i> in non‐small cell lung cancer

Brent Graham, Jayne Curry, Tomoko Smyth et al. · Cancer Science · 2011 · 80 citations · Full text

Medicine, Oncology, Pharmacology +13

Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance

Laura Ramos Garcia, Tencho Tenev, Richard Newman et al. · Nature Communications · 2021 · 77 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16