Naoko Sakai

MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil

Hiroshi Hirai, Tsuyoshi Arai, Megumu Okada et al. · Cancer Biology & Therapy · 2010 · 236 citations · Full text

Medicine, Oncology, Pharmacology +17

Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

Yuichiro Mita, Kaho Nakayama, Shogo Inari et al. · Nature Communications · 2017 · 164 citations · Full text

Medicine, Endocrinology, Molecular Biology +17

Magnetic Properties of All‐Organic Liquid Crystals Containing a Chiral Five‐Membered Cyclic Nitroxide Unit within the Rigid Core

Naohiko Ikuma, Rui Tamura, Satoshi Shimono et al. · Angewandte Chemie International Edition · 2004 · 112 citations · Full text

Natural Sciences, Chemistry, Physics +17

Microbial hydrolysis as a potent method for the preparation of optically active nitriles, amides and carboxylic acids

Hideaki Kakeya, Naoko Sakai, Takeshi Sugai et al. · Tetrahedron Letters · 1991 · 108 citations

Life Sciences, Medicinal Chemistry, Microbiology +10

Pharmacological Characterization of a New, Orally Active and Potent Allosteric Metabotropic Glutamate Receptor 1 Antagonist, 4-[1-(2-Fluoropyridin-3-yl)-5-methyl-1 H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2 H)-carboxamide (FTIDC)

Gentaroh Suzuki, Toshifumi Kimura, Akio Satow et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 67 citations

Medicine, Medicinal Chemistry, Pharmacology +13