D.E. Mortenson

“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates

D.E. Mortenson, Gabriel J. Brighty, Lars Plate et al. · Journal of the American Chemical Society · 2017 · 299 citations · Full text

Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue

Wentao Chen, Jiajia Dong, Lars Plate et al. · Journal of the American Chemical Society · 2016 · 288 citations · Full text

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

Amado Carreras‐Sureda, Fabián Jaña, Hery Urra et al. · Nature Cell Biology · 2019 · 263 citations · Full text

Signal Transduction, Molecular Physiology, Mitochondrial Function +12

Enzyme-Amplified Array Sensing of Proteins in Solution and in Biofluids

Oscar R. Miranda, Hung‐Ting Chen, Chang‐Cheng You et al. · Journal of the American Chemical Society · 2010 · 212 citations

Engineering, Analytical Microsystems, Biosensors +18

Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery

Gabriel J. Brighty, Rachel C. Botham, Suhua Li et al. · Nature Chemistry · 2020 · 140 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Medicine +12