Concepedia

Craig Karr

CK

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Publications

13

Citations

1.3K

H-Index

13

Active since

1996

Affiliations

Institute for Biomedicine(Current)

Andover Eye Associates

Moffitt Cancer Center

Memorial Sloan Kettering Cancer Center

Eisai (United States)

Craig Karr is an author at Institute for Biomedicine specializing in medicine, tumor biology, and drug discovery.

Top concepts

Publications per year

1996–2022

13

Publications

13

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Michael Seiler, Akihide Yoshimi, Rachel Darman et al. · Nature Medicine · 2018 · 491 citations · Full text

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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

Teng Teng, Jennifer Tsai, Xiaoling Puyang et al. · Nature Communications · 2017 · 147 citations · Full text

H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma

Jaya Julie Joshi, Heather Coffey, Erik Corcoran et al. · Cancer Research · 2017 · 144 citations

The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action

Lorenzo I. Finci, Xiaofeng Zhang, Xiuliang Huang et al. · Genes & Development · 2018 · 109 citations · Full text

Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

Xiaoling Puyang, Craig Furman, Guo Zhu Zheng et al. · Cancer Discovery · 2018 · 109 citations

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