Krystyna J. Dillon

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature · 2005 · 6.7K citations

Life Sciences, Genetics, Molecular Biology +16

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2<i>H</i>-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1

Keith Menear, Claire Adcock, Robert Boulter et al. · Journal of Medicinal Chemistry · 2008 · 586 citations · Full text

Medicine, Oncology, Pharmacology +16

Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase

Vincent M. Loh, Xiaoling Cockcroft, Krystyna J. Dillon et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 92 citations · Full text

Life Sciences, Chemistry, Medicinal Chemistry +13

Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase

Xiaoling Cockcroft, Krystyna J. Dillon, Lesley Dixon et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 88 citations · Full text

Life Sciences, Chemistry, Medicinal Chemistry +13

Technical Note: A FlashPlate Assay for the Identification of PARP-1 Inhibitors

Krystyna J. Dillon, Graeme C.M. Smith, Niall M.B. Martin · SLAS DISCOVERY · 2003 · 46 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17