Xuhai Be

Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7

Thomas Kornecook, Ruoyuan Yin, Stephen M. Altmann et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 52 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Discovery of <i>N</i>-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of Aurora Kinases with Activity against Multidrug-Resistant Cancer Cell Lines

Stephanie Geuns-Meyer, Victor J. Cee, Holly L. Deak et al. · Journal of Medicinal Chemistry · 2015 · 45 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Prediction of Vss from In Vitro Tissue-Binding Studies

Loren Berry, Jonathan Roberts, Xuhai Be et al. · Drug Metabolism and Disposition · 2009 · 44 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

Victor J. Cee, Laurie B. Schenkel, Brian L. Hodous et al. · Journal of Medicinal Chemistry · 2010 · 37 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of Tarantula Venom-Derived Na_V1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Bin Wu, Justin K. Murray, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17