Global Nav1.7 Knockout Mice Recapitulate the Phenotype of Human Congenital Indifference to Pain

Jacinthe Gingras, Sarah E. Smith, David J. Matson, +11

PLoS ONE

Pain MedicineImmunologyNeuropathic PainMolecular PainPain Syndrome +15

Pharmacological Characterization and Identification of Amino Acids Involved in the Positive Modulation of Metabotropic Glutamate Receptor Subtype 2

Hervé Schaffhauser, Blake A. Rowe, Sylvia Morales, +10

Molecular Pharmacology

PAC1 receptor blockade reduces central nociceptive activity: new approach for primary headache?

Jan Hoffmann, Silke Miller, Margarida Martins-Oliveira, +12

Pain

Pain MedicineNeuropathic PainMolecular PainPharmacotherapyPrimary Headaches +19

A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study

Ruoyuan Yin, Edward D. French

Brain Research Bulletin

Behavioral NeuroscienceNeuroanatomyNeurophysiologyPhysiologyNon-dopamine Neurons +9

Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7

Thomas Kornecook, Ruoyuan Yin, Stephen M. Altmann, +20

Journal of Pharmacology and Experimental Therapeutics

Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

Bryan D. Moyer, Justin K. Murray, Joseph Ligutti, +15

PLoS ONE

Pharmacological CharacterizationMolecular BiologyMolecular PainPharmacotherapyMolecular Pharmacology +15

Structure–activity relationship (SAR) investigations of tetrahydroquinolines as BKCa agonists

Vijay Gore, Vu V., Ruoyuan Yin, +4

Bioorganic & Medicinal Chemistry Letters

Structure–activity RelationshipMolecular PharmacologyBiochemistryMedicineMechanism Of Action +2

Voltage-gated sodium channel function and expression in injured and uninjured rat dorsal root ganglia neurons

Ruoyuan Yin, Dong Liu, Mark Chhoa, +6

International Journal of Neuroscience

Peripheral Nerve InjurySynaptic TransmissionNeuropathic PainMolecular PainNeurotransmission +18

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

Sonya G. Lehto, Andy Weyer, Beth D. Youngblood, +11

Molecular Pain