Kazunari Hattori

In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

Takeshi Noshi, Mitsutaka Kitano, K. Taniguchi et al. · Antiviral Research · 2018 · 376 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Predicting human liver microsomal stability with machine learning techniques

Yojiro Sakiyama, Hitomi Yuki, Takashi Moriya et al. · Journal of Molecular Graphics and Modelling · 2007 · 96 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +12

Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively

Kensaku Shojima, Akira Sato, Hideaki Hanaki et al. · Scientific Reports · 2015 · 70 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics

Felix Deanda, Kendra E. Hightower, Robert T. Nolte et al. · PLoS ONE · 2013 · 56 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacotherapy +17

Conformational Restriction Approach to β-Secretase (BACE1) Inhibitors: Effect of a Cyclopropane Ring To Induce an Alternative Binding Mode

Shuji Yonezawa, Takahiko Yamamoto, Hidekuni Yamakawa et al. · Journal of Medicinal Chemistry · 2012 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17