Shuji Yonezawa

Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based β-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial

Yuji Koriyama, Akihiro Hori, Hisanori Ito et al. · Journal of Medicinal Chemistry · 2021 · 54 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Conformational Restriction Approach to β-Secretase (BACE1) Inhibitors: Effect of a Cyclopropane Ring To Induce an Alternative Binding Mode

Shuji Yonezawa, Takahiko Yamamoto, Hidekuni Yamakawa et al. · Journal of Medicinal Chemistry · 2012 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Expansion of Antibacterial Spectrum of Muraymycins toward <i>Pseudomonas aeruginosa</i>

Yusuke Takeoka, Tetsuya Tanino, Mitsuaki Sekiguchi et al. · ACS Medicinal Chemistry Letters · 2014 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Total Synthesis of Terprenin, a Highly Potent and Novel Immunoglobulin E Antibody Suppressant

Kenji Kawada, Akinori Arimura, Tatsuo Tsuri et al. · Angewandte Chemie International Edition · 1998 · 41 citations

Pharmacy, Immunology, Medicinal Chemistry +7

Iron(<scp>III</scp>)-catalysed nitration of non-activated and moderately activated arenes with nitrogen dioxide–molecular oxygen under neutral conditions

Hitomi Suzuki, Shuji Yonezawa, Nobuaki Nonoyama et al. · Journal of the Chemical Society Perkin Transactions 1 · 1996 · 40 citations

Natural Sciences, Chemistry, Catalysis +9