Mitsuaki Sekiguchi

2′-O,4′-C-Methylene Bridged Nucleic Acid Modification Promotes Pyrimidine Motif Triplex DNA Formation at Physiological pH

Hidetaka Torigoe, Yoshiyuki Hari, Mitsuaki Sekiguchi et al. · Journal of Biological Chemistry · 2001 · 143 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Triplex-forming enhancement with high sequence selectivity by single 2′-O,4′-C-methylene bridged nucleic acid (2′,4′-BNA) modification

Satoshi Obika, Yoshiyuki Hari, Tomomi Sugimoto et al. · Tetrahedron Letters · 2000 · 67 citations

Life Sciences, Molecular Biology, Nucleic Acid Biochemistry +14

A 2′,4′-Bridged Nucleic Acid Containing 2-Pyridone as a Nucleobase: Efficient Recognition of a C⋅G Interruption by Triplex Formation with a Pyrimidine Motif

Satoshi Obika, Yoshiyuki Hari, Mitsuaki Sekiguchi et al. · Angewandte Chemie International Edition · 2001 · 65 citations

Pharmacy, Molecular Biology, Molecular Diagnostics +16

An Efficient Approach to the Discovery of Potent Inhibitors against Glycosyltransferases

Kensaku Hosoguchi, Takahiro Maeda, Jun‐ichi Furukawa et al. · Journal of Medicinal Chemistry · 2010 · 54 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Expansion of Antibacterial Spectrum of Muraymycins toward <i>Pseudomonas aeruginosa</i>

Yusuke Takeoka, Tetsuya Tanino, Mitsuaki Sekiguchi et al. · ACS Medicinal Chemistry Letters · 2014 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15