Brian Rago

Where Did the Linker-Payload Go? A Quantitative Investigation on the Destination of the Released Linker-Payload from an Antibody-Drug Conjugate with a Maleimide Linker in Plasma

Cong Wei, Guodong Zhang, Tracey Clark et al. · Analytical Chemistry · 2016 · 105 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Dose‐Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs

Daiki Mori, Emi Kimoto, Brian Rago et al. · Clinical Pharmacology & Therapeutics · 2019 · 102 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Optimization of Tubulysin Antibody–Drug Conjugates: A Case Study in Addressing ADC Metabolism

L. Nathan Tumey, Carolyn A. Leverett, Beth C. Vetelino et al. · ACS Medicinal Chemistry Letters · 2016 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates

L. Nathan Tumey, Fengping Li, Brian Rago et al. · The AAPS Journal · 2017 · 67 citations

Pharmacy, Chemical Biology, Pharmaceutics +14

Natural Product Splicing Inhibitors: A New Class of Antibody–Drug Conjugate (ADC) Payloads

Sujiet Puthenveetil, Frank Loganzo, Haiyin He et al. · Bioconjugate Chemistry · 2016 · 66 citations

Pharmacy, Oncology, Pharmacology +17