Keith Jendza

Discovery of 4-((2 <i>S</i> ,4 <i>S</i> )-4-Ethoxy-1-((5-methoxy-7-methyl-1 <i>H</i> -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases

Nello Mainolfi, Takeru Ehara, Rajeshri G. Karki et al. · Journal of Medicinal Chemistry · 2020 · 60 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Discovery of <i>N</i>-(1-Methyl-5-(trifluoromethyl)-1<i>H</i>-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1<i>H</i>-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration

Christopher M. Adams, Karen Anderson, Gerald D. Artman et al. · Journal of Medicinal Chemistry · 2018 · 41 citations · Full text

Medicine, Ophthalmology, Pharmacology +16

The Versatility of α-Chloropropargyl Phenyl Sulfide Affords High Stereo- and Regioselectivities in Indium-Promoted Coupling Reactions under Mild Conditions

Thomas M. Mitzel, Carolyn Palomo, Keith Jendza · The Journal of Organic Chemistry · 2001 · 25 citations

Natural Sciences, Chemistry, Catalysis +11

A Reliable Synthesis of 3-Amino-5-Alkyl and 5-Amino-3-Alkyl Isoxazoles

Nello Mainolfi, Leland Johnson, James J. Powers et al. · Synthesis · 2012 · 21 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

A small-molecule inhibitor of C5 complement protein

Keith Jendza, Mitsunori Kato, Michael Salcius et al. · Nature Chemical Biology · 2019 · 21 citations

Life Sciences, Immunology, Medicinal Chemistry +14