Seth E. Karol

Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study

Seth E. Karol, Thomas Alexander, Amit Budhraja et al. · The Lancet Oncology · 2020 · 162 citations · Full text

Medicine, Hematology, Pharmacology +16

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

Steven W. Paugh, Erik Bonten, Daniel Savic et al. · Nature Genetics · 2015 · 160 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Clinical Significance of Novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease–Directed Therapy

Sima Jeha, John Choi, Kathryn G. Roberts et al. · Blood Cancer Discovery · 2021 · 152 citations · Full text

Medicine, Hematology, Oncology +17

Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia

Seth E. Karol, Wenjian Yang, Sara L. Van Driest et al. · Blood · 2015 · 119 citations · Full text

Medicine, Genetics, Oncology +14

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response

Shawn H. R. Lee, Wenjian Yang, Yoshihiro Gocho et al. · Nature Medicine · 2023 · 97 citations · Full text

Medicine, Oncology, Pharmacology +17