Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways

Poyil Pratheeshkumar, Amit Budhraja, Young‐Ok Son, +10

PLoS ONE

Ex Vivo AngiogenesisUrologyAngiogenesisChemoprevention StrategyMedicine +12

Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study

Seth E. Karol, Thomas Alexander, Amit Budhraja, +14

The Lancet Oncology

Dose-escalation StudyHematological MalignancyPediatric HematologyMedicineMixed-phenotype Acute Leukemia +7

Cadmium induces autophagy through ROS-dependent activation of the LKB1–AMPK signaling in skin epidermal cells

Young‐Ok Son, John Andrew Hitron, Zhuo Zhang, +5

Toxicology and Applied Pharmacology

Cell AutophagySkin Epidermal CellsSignal TransductionMolecular PhysiologyCadmium Induces +10

Luteolin Inhibits Human Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis

Poyil Pratheeshkumar, Young‐Ok Son, Amit Budhraja, +11

PLoS ONE

Mmp-9 ExpressionsTumor BiologyAngiogenesisMatrix BiologyRadiation Oncology +15

Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling

Young‐Ok Son, Lei Wang, Poyil Pratheeshkumar, +5

Toxicology and Applied Pharmacology

Signaling PathwayCell RegulationCell SignalingMedicineRos-dependent Activation +11

NADPH Oxidase Activation Is Required in Reactive Oxygen Species Generation and Cell Transformation Induced by Hexavalent Chromium

Xin Wang, Young‐Ok Son, Qingshan Chang, +8

Toxicological Sciences

Lipid PeroxidationMolecular BiologyCell DeathNadph Oxidase ActivationRedox Biology +16

Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways

Ning Gao, Amit Budhraja, Senping Cheng, +6

Cell Death and Disease

Chemoprevention StrategyApoptosisCell DeathTumor BiologyMedicinal Chemistry +17

Apigenin Induces Apoptosis in Human Leukemia Cells and Exhibits Anti-Leukemic Activity <i>In Vivo</i>

Amit Budhraja, Ning Gao, Zhuo Zhang, +8

Molecular Cancer Therapeutics

Quercetin Induces Tumor-Selective Apoptosis through Downregulation of Mcl-1 and Activation of Bax

Senping Cheng, Ning Gao, Zhuo Zhang, +7

Clinical Cancer Research

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis

Guobing� Li, Jing Zhou, Amit Budhraja, +8

Oncotarget