Erik Bonten

Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis.

Erik Bonten, Aarnoud C. van der Spoel, Maarten Fornerod et al. · Genes & Development · 1996 · 307 citations · Full text

Glycobiology, Molecular Biology, Protein Expression +16

Neuraminidase 1 Is a Negative Regulator of Lysosomal Exocytosis

Gouri Yogalingam, Erik Bonten, Diantha van de Vlekkert et al. · Developmental Cell · 2008 · 175 citations · Full text

Protein Function, Natural Sciences, Pathogenesis +6

Human lysosomal protective protein has cathepsin A-like activity distinct from its protective function

Niels Galjart, Hans Morreau, Rob Willemsen et al. · Journal of Biological Chemistry · 1991 · 159 citations · Full text

Protein Secretion, Protective Function, Autophagy +16

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

Steven W. Paugh, Erik Bonten, Daniel Savic et al. · Nature Genetics · 2015 · 158 citations · Full text

Casp1 Cleavage, Signal Transduction, Nalp3 Inflammasome Upregulation +8

Novel mutations in lysosomal neuraminidase identify functional domains and determine clinical severity in sialidosis

Erik Bonten · Human Molecular Genetics · 2000 · 148 citations

Functional Domains, Molecular Diagnostic Techniques, Neuraminidase Gene +15