Aarnoud C. van der Spoel

Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

Giovanni D’Angelo, Elena Polishchuk, Giuseppe Di Tullio et al. · Nature · 2007 · 393 citations · Full text

Biosynthesis, G Protein-coupled Receptor, Medicine +5

Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis.

Erik Bonten, Aarnoud C. van der Spoel, Maarten Fornerod et al. · Genes & Development · 1996 · 307 citations · Full text

Glycobiology, Molecular Biology, Protein Expression +16

Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson’s disease

Mylene Huebecker, Elizabeth B. Moloney, Aarnoud C. van der Spoel et al. · Molecular Neurodegeneration · 2019 · 162 citations · Full text

Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A

Aarnoud C. van der Spoel · The EMBO Journal · 1998 · 134 citations · Full text

Protein Secretion, Protein Function, Biochemistry +10

Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis

Mariona Rabionet, Aarnoud C. van der Spoel, Chia-Chen Chuang et al. · Journal of Biological Chemistry · 2008 · 112 citations · Full text

Spermatogenesis, Fertility, Genetics +22